Hydroxide → tert-butyl N-[1-[5-bromo-3-(butanoylamino)-1H-pyrrolo[2,3-b]pyridin-4-yl]piperidin-3-yl]carbamate

HRID 957748Notes

Reaction equation

[C:1]([CH2:2][CH2:3][CH3:4])(=[O:5])[Cl:6].[CH2:51]1[O:52][CH2:53][CH2:54][CH2:55]1.[CH3:32][CH2:33][N:34]([CH2:35][CH3:36])[CH2:37][CH3:38].[CH3:44][N:45]1[CH2:46][CH2:47][CH2:48][C:49]1=[O:50].[Cl:41][CH2:42][Cl:43].[Li+:40].[NH2:7][c:8]1[cH:9][nH:10][c:11]2[n:12][cH:13][c:14]([Br:31])[c:15]([N:17]3[CH2:18][CH:19]([NH:23][C:24]([O:25][C:26]([CH3:27])([CH3:28])[CH3:29])=[O:30])[CH2:20][CH2:21][CH2:22]3)[c:16]12.[OH-:39]>>[C:1]([CH2:2][CH2:3][CH3:4])(=[O:5])[NH:7][c:8]1[cH:9][nH:10][c:11]2[n:12][cH:13][c:14]([Br:31])[c:15]([N:17]3[CH2:18][CH:19]([NH:23][C:24]([O:25][C:26]([CH3:27])([CH3:28])[CH3:29])=[O:30])[CH2:20][CH2:21][CH2:22]3)[c:16]12