Chloride → Benzyl 4-(3-bromophenyl)-5,6-dihydropyridine-1(2H)-carboxylate

HRID 96044Notes

Reaction equation

HRID 96044 reaction equation
[Br:8][c:9]1[cH:10][cH:11][cH:12][c:13]([Br:14])[cH:15]1.[CH2:33]1[O:34][CH2:35][CH2:36][CH2:37]1.[CH:4]([Mg+:5])([CH3:6])[CH3:7].[Cl-:1].[Cl-:3].[Li+:2].[O:16]=[C:17]1[CH2:18][CH2:19][N:20]([C:23](=[O:24])[O:25][CH2:26][c:27]2[cH:28][cH:29][cH:30][cH:31][cH:32]2)[CH2:21][CH2:22]1>>[c:9]1([C:17]2=[CH:18][CH2:19][N:20]([C:23](=[O:24])[O:25][CH2:26][c:27]3[cH:28][cH:29][cH:30][cH:31][cH:32]3)[CH2:21][CH2:22]2)[cH:10][cH:11][cH:12][c:13]([Br:14])[cH:15]1

Participants

7

Reactant 6

HCID 312Chloride2×HCID 79271,3-DibromobenzeneHCID 8028TetrahydrofuranHCID 28486Lithium ionHCID 643496Benzyl 4-oxopiperidine-1-carboxylateHCID 178461726HCID 178461726, compound

Product 1

HCID 57969601Benzyl 4-(3-bromophenyl)-5,6-dihydropyridine-1(2H)-carboxylate

Sources & evidence

ORD record
ord-1161bd462e5a4b29be8fde8341d421d3
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (2/10)

Reaction notes

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