Dimethylformamide → 4-(3-bromo-phenylethynyl)-1H-pyrrole-2-carbonitrile

HRID 97075Notes

Reaction equation

HRID 97075 reaction equation
[Br:16][c:17]1[cH:18][c:19]([C:23]#[CH:24])[cH:20][cH:21][cH:22]1.[C:1](#[N:2])[c:3]1[nH:4][cH:5][c:6]([I:8])[cH:7]1.[CH3:25][N:26]([CH3:27])[CH:28]=[O:29].[CH3:30][CH2:31][O:32][C:33](=[O:34])[CH3:35].[CH3:9][CH2:10][N:11]([CH2:12][CH3:13])[CH2:14][CH3:15].[Cu:36][I:37]>>[C:1](#[N:2])[c:3]1[nH:4][cH:5][c:6]([C:24]#[C:23][c:19]2[cH:18][c:17]([Br:16])[cH:22][cH:21][cH:20]2)[cH:7]1

Participants

7

Reactant 6

HCID 6228DimethylformamideHCID 8471TriethylamineHCID 8857Ethyl AcetateHCID 24350Copper(1+) iodide; Copper(I) iodide; Cuprous iodide; Cuprous iodide (CuI)HCID 114808181-Bromo-3-ethynylbenzeneHCID 132203124-Iodo-1H-pyrrole-2-carbonitrile

Product 1

HCID 686993714-(3-bromo-phenylethynyl)-1H-pyrrole-2-carbonitrile

Sources & evidence

ORD record
ord-35070c6be8d842a8811b38c4d557c53d
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (2/10)

Reaction notes

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