Methyl iodide → HCID 18507447, compound

Reaction equation

CO[C:3]([C:5]1[O:6][CH:7]=[C:8]([C:10]#[N:11])[CH:9]=1)=O.[H-].[Na+].CI.[N+]([O-])(O)=O.[NH2:20][C:21]([NH2:23])=[NH:22].[C:24](=[S:26])=S>C1COCC1.CS(C)=O.CN(C=O)C.C(N(CC)CC)C.C(#N)C>[NH2:22][C:21]1[N:23]=[C:3]([C:5]2[O:6][CH:7]=[C:8]([C:10]#[N:11])[CH:9]=2)[C:8]([C:10]#[N:11])=[C:7]([S:26][CH3:24])[N:20]=1

Participants

Reactant 5

HCID 6328Methyl iodide

HCID 6348Carbon Disulfide

HCID 10481Guanidine Nitrate

HCID 24758Sodium hydride2×

HCID 45090083Methyl 4-cyanofuran-2-carboxylate

Product 1

HCID 18507447HCID 18507447, compound

Reagents, catalysts & solvents 5

Procedure

From 4-cyano-furan-2-carboxylic acid methyl ester with sodium hydride and acetonitrile in THF. Then treatment with sodium hydride, carbon disulphide and methyl iodide in DMSO. Then treatment with guanidine nitrate and triethylamine in DMF. EI-MS m/e (%): 257 (M+, 35), 256 ([M—H]+, 100).