Ammonia → Methylamide

Reaction equation

CN.[CH2:3]([NH:5]CC)C.[CH3:8][N:9]([CH3:13])[CH2:10][CH2:11][NH2:12].NN.[NH2:16][OH:17].N1CCOCC1.C(N1CCCCC1)C.OCCN1CCCCC1.OCCN.N>>[CH3:3][NH-:5].[CH3:8][N:9]([CH3:13])[CH2:10][CH2:11][NH-:12].[OH:17][NH-:16]

Participants

Reactant 10

HCID 222Ammonia

HCID 700Ethanolamine

HCID 787Hydroxylamine

HCID 6329Methylamine

HCID 8021Diethylamine

HCID 8083Morpholine

HCID 9321Hydrazine

HCID 13007N-Ethylpiperidine

Procedure

Similarly, when methylamine, diethylamine, β-dimethylaminoethylamine, hydrazine, hydroxylamine, morpholine, N-ethylpiperidine, N-(β-hydroxyethyl)-piperidine, or β-hydroxyethylamine are used in place of ammonia in the above example, there are obtained the corresponding N-methylamide, N-diethylamide, N-(β-dimethylaminoethyl)-amide, hydrazide, N-hydroxyamide, morpholide, 4-ethylpiperidide, 4-(β-hydroxyethyl)-piperidide, or β-hydroxylethylamide, respectively.