Tetrahydrofuran → 2-[(Trimethylsilyl)ethynyl]benzaldehyde

HRID 957382

Reaction equation

HRID 957382 reaction equation
[Br:1][c:2]1[c:3]([CH:4]=[O:5])[cH:6][cH:7][cH:8][cH:9]1.[CH3:10][Si:11]([CH3:12])([CH3:13])[C:14]#[CH:15].[CH3:16][CH2:17][N:18]([CH2:19][CH3:20])[CH2:21][CH3:22].[CH3:23][CH2:24][O:25][C:26](=[O:27])[CH3:28].[CH3:34][CH2:35][CH2:36][CH2:37][CH2:38][CH3:39].[Cu:40][I:41].[O:29]1[CH2:30][CH2:31][CH2:32][CH2:33]1>>[c:2]1([C:15]#[C:14][Si:11]([CH3:10])([CH3:12])[CH3:13])[c:3]([CH:4]=[O:5])[cH:6][cH:7][cH:8][cH:9]1

Participants

8

Reactant 7

HCID 8028TetrahydrofuranHCID 8058HexaneHCID 8471TriethylamineHCID 8857Ethyl AcetateHCID 24350Copper(1+) iodide; Copper(I) iodide; Cuprous iodide; Cuprous iodide (CuI)HCID 66111TrimethylsilylacetyleneHCID 811292-Bromobenzaldehyde

Product 1

HCID 27716412-[(Trimethylsilyl)ethynyl]benzaldehyde

Sources & evidence

ORD record
ord-d8a1fae913e642318c4efba5f2dcd187
Source dataset
Validation data from https://doi.org/10.1039/C8SC04228D

Linked notes

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