L-Phenylglycine
기본 정보
- CAS
2935-35-5- 표준 SMILES
N[C@H](C(=O)O)c1ccccc1- InChIKey
ZGUNAGUHMKGQNY-ZETCQYMHSA-N- 분자식
- C8H9NO2
- 평균 분자량
- 151.16 g/mol
- 단동위원소 질량
- 151.06332853
개요
L-alpha-phenylglycine is the S stereoisomer of alpha-phenylglycine. It is an enantiomer of a D-alpha-phenylglycine. It is a tautomer of a L-alpha-phenylglycine zwitterion.
이름 및 식별자
- 우선 이름
- L-Phenylglycine
- IUPAC
- (2S)-2-amino-2-phenylacetic acid
- 영어명
- L-Phenylglycine
- 분자식
- C8H9NO2
- 분자량
- 151.16
이름 및 동의어
L-Phenylglycine2935-35-5L-(+)-2-PhenylglycinePhenylglycine, L-Glycine, 2-phenyl-, L-L-(+)-alpha-Aminophenylacetic acid3I753R0XI6Benzeneacetic acid, alpha-amino-, (alphaS)-DTXSID801022916NSC-206293Benzeneacetic acid, alpha-amino-, (S)-L-Phg amino acid
이름 더 보기
PHENYLGLYCINEL-PhgPhg-OHL-Phg-OHL-(+)-PHENYLGLYCINEH-L-PHG-OHL-Aminophenyl
RefChem:8617402-phenylglycine, (L)-DTXCID901507343220-909-8H-Phg-Oh(S)-2-Amino-2-phenylacetic acid(2S)-2-amino-2-phenylacetic acidL-2-Phenylglycine
데이터베이스 식별자
- CAS
2935-35-5- PubChem CID
- 99291
- DTXSID
DTXSID801022916- ChEMBL
CHEMBL378605- ChEBI
CHEBI:439819- UNII
- 3I753R0XI6
- EC Number
- 220-909-8
- Nikkaji
- J7.943J
물성
구조 계산 물성
- XLogP
- -1.7
- 극성 표면적
- 63.3 Ų
- 수소 결합 공여자 수
- 2
- 수소 결합 수용자 수
- 3
- 회전 가능 결합 수
- 2
- 무거운 원자 수
- 11
- 형식 전하
- 0
- 복잡도
- 141
물리화학적 성질
- 녹는점
- 300 °C · >300 °C(lit.)
- 끓는 점
- 273.17 °C · 273.17°C (rough estimate)
- 밀도
- 1.2023 · 1.2023 (rough estimate)
- 굴절률
- 158 ° · 158 ° (C=1, 1mol/L HCl)
- 인화점
- 150 °C · 150 °C
- 저장 조건
- Keep in dark place,Inert atmosphere,Room temperature
- 용해도
- 에 용해됨수성 산, 수성 염기
- 산도 계수 (pKa)
- 1.83 · 1.83(at 25℃)
- 물리적 상태
- 미세 결정성 분말
- 색상
- 하얀색
- Merck
- 14 · 14,7291
- BRN
- 2208675 · 2208675
- 주요 응용
- 펩타이드 합성
- InChI
- 1S/C8H9NO2/c9-7(8(10)11)6-4-2-1-3-5-6/h1-5,7H,9H2,(H,10,11)/t7-/m0/s1
- InChIKey
- ZGUNAGUHMKGQNY-ZETCQYMHSA-N
- SMILES
- N[C@H](C(O)=O)c1ccccc1
- EPA
- L-Phenylglycine (2935-35-5)
화학적 성질
안전 및 규제
안전 정보는 참고용이며, 공급업체의 물질안전보건자료(SDS), 관련 법규 및 전문가 평가를 대체하지 않습니다.
GHS 분류
GHS Classification
This chemical does not meet GHS hazard criteria for 33.3% (1 of 3) of reports.
Warning
H315 (66.7%): Causes skin irritation [Warning Skin corrosion/irritation]
P261, P264, P264+P265, P271, P280, P302+P352, P304+P340, P305+P351+P338, P319, P321, P332+P317, P337+P317, P362+P364, P403+P233, P405, and P501 (click each P-code to see the statement)
Aggregated GHS information provided per 3 reports by companies from 3 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.
유해성 정보
Regulatory InformationBenzeneacetic acid, .alpha.-amino-, (.alpha.S)-: Does not have an individual approval but may be used under an appropriate group standard
Hazard Classes and CategoriesSkin Irrit. 2 (66.7%)
안전 데이터
- wgk
- 3
- tsca
- TSCA listed
- HS 번호
- 29224995
- safety_code
- 22-24/25
- 기존화학 물질
- KE-28376
- 스토리지 클래스
- 11 - Combustible Solids
화학 및 산업
용도 및 제조
General Manufacturing InformationBenzeneacetic acid, .alpha.-amino-, (.alpha.S)-: ACTIVE
응용 분야
개요L-Phenylglycine is an amide that belongs to the group of pyridoxal phosphate analogues. It has been shown to be a response element for enzymes and natural compounds in Escherichia coli and Saccharomyces cerevisiae. It inhibits aminotransferase activity, dopamine synthesis, and microbial metabolism in these organisms. This compound also has a structural analysis that includes x-ray diffraction data, which can be used to identify its three-dimensional structure.
용도L-(+)-2-Phenylglycine is a derivative of Glycine (G615990), the smallest of all the amino acids, and is also used to treat schizophrenia, stroke, and benign prostatic hyperplasia. L-(+)-2-Phenylglycine is also used as an N-linked side chain of an SMTP (Stachybotrys microspora tripenyl phenols) congener, which was potent in enhancing plasminogen activation in S. microspora.
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