1-Phenylpiperazine → HCID 14763435, compound

HRID 1087820Notes

Reaction equation

HRID 1087820 reaction equation
CN(C)C[CH2:4][CH2:5][NH:6][C:7]([N:9]1[CH2:14][CH2:13][N:12]([C:15]2[CH:20]=[CH:19][CH:18]=[CH:17][CH:16]=2)[CH2:11][CH2:10]1)=[O:8].[C:22](N1C=CN=C1)([N:24]1C=CN=[CH:25]1)=O.CN(CCN)C.C1(N2CCNCC2)C=CC=CC=1>O1CCCC1>[CH3:22][N:24]([CH3:25])[CH2:4][CH2:5][NH:6][C:7]([N:9]1[CH2:10][CH2:11][N:12]([C:15]2[CH:16]=[CH:17][CH:18]=[CH:19][CH:20]=2)[CH2:13][CH2:14]1)=[O:8]

Participants

6

Reactant 4

HCID 70961-PhenylpiperazineHCID 66053N,N-DimethylethylenediamineHCID 682631,1'-CarbonyldiimidazoleHCID 14763436HCID 14763436, compound

Product 1

HCID 14763435HCID 14763435, compoundYield 43%

Reagents, catalysts & solvents 1

HCID 8028TetrahydrofuranSolvent

Procedure

This compound was prepared according to the procedure used to synthesize the compound of Example 5. A mixture of 5.7 g (0.035 mole) of 1,1'-carbonyldiimidazole, 3.0 g (0.034 mole) of unsym-dimethylethylenediamine and 4.9 g (0.03 mole) of 1-phenylpiperazine in a total of 200 ml of tetrahydrofuran gave 3.6 g (43%) of title compound as a white powder, m.p. 88°-90° C., after recrystallization from diisopropyl ether.

Workup

  1. customThis compound was prepared

Sources & evidence

ORD record
ord-0cd46503136c462aa0edc6b73b6137fa
Source dataset
uspto-grants-1990_10
Patent number
US04960776

Reaction notes

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