Ammonium → N-[1-(1,3-benzodioxol-5-yl)-3,4-bis[[tert-butyl(dimethyl)silyl]oxy]butan-2-yl]-2-methylpropane-2-sulfinamide

HRID 1113154Notes

Reaction equation

HRID 1113154 reaction equation
[C:22]([CH3:23])([CH3:24])([CH3:25])[Si:26]([O:27][CH:28]([CH:29]=[N:30][S:31](=[O:32])[C:33]([CH3:34])([CH3:35])[CH3:36])[CH2:37][O:38][Si:39]([CH3:40])([CH3:41])[C:42]([CH3:43])([CH3:44])[CH3:45])([CH3:46])[CH3:47].[CH2:48]1[O:49][CH2:50][CH2:51][CH2:52]1.[CH3:14][N:15]([CH3:16])[CH2:17][CH2:18][N:19]([CH3:20])[CH3:21].[CH3:53][CH2:54][O:55][C:56](=[O:57])[CH3:58].[Cl-:59].[Cl:3][CH2:4][c:5]1[cH:6][c:7]2[c:8]([cH:12][cH:13]1)[O:9][CH2:10][O:11]2.[I:2].[Mg:1].[NH4+:60]>>[CH2:4]([c:5]1[cH:6][c:7]2[c:8]([cH:12][cH:13]1)[O:9][CH2:10][O:11]2)[CH:29]([CH:28]([O:27][Si:26]([C:22]([CH3:23])([CH3:24])[CH3:25])([CH3:46])[CH3:47])[CH2:37][O:38][Si:39]([CH3:40])([CH3:41])[C:42]([CH3:43])([CH3:44])[CH3:45])[NH:30][S:31](=[O:32])[C:33]([CH3:34])([CH3:35])[CH3:36]

Participants

10

Reactant 9

HCID 223AmmoniumHCID 312ChlorideHCID 8028TetrahydrofuranHCID 8037N,N,N',N'-TetramethylethylenediamineHCID 8857Ethyl AcetateHCID 24841Hydrogen iodideHCID 887131,3-Benzodioxole, 5-(chloromethyl)-HCID 5462224MagnesiumHCID 74961661N-[2,3-bis[[tert-butyl(dimethyl)silyl]oxy]propylidene]-2-methylpropane-2-sulfinamide

Product 1

HCID 77234473N-[1-(1,3-benzodioxol-5-yl)-3,4-bis[[tert-butyl(dimethyl)silyl]oxy]butan-2-yl]-2-methylpropane-2-sulfinamide

Sources & evidence

ORD record
ord-880eaabcf00c40f59f3e3d9042567a1f
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (7/10)

Reaction notes

Loading…