Hydrochloric Acid → 2-(3-(2-(4-fluorobenzylamino)-2-oxoethyl)-2-oxoimidazolidin-1-yl)-4-methyl-N-(pyridin-3-ylmethyl)thiazole-5-carboxamide

HRID 1113996Notes

Reaction equation

HRID 1113996 reaction equation
[CH2:39]([N:40]=[C:41]=[N:42][CH2:43][CH2:44][CH2:45][N:46]([CH3:47])[CH3:48])[CH3:49].[CH3:67][N:68]([CH3:69])[CH:70]=[O:71].[CH3:72][CH2:73][O:74][C:75](=[O:76])[CH3:77].[CH:50]([N:51]([CH2:52][CH3:53])[CH:54]([CH3:55])[CH3:56])([CH3:57])[CH3:58].[ClH:38].[F:1][c:2]1[cH:3][cH:4][c:5]([CH2:6][NH:7][C:8]([CH2:9][N:10]2[C:11](=[O:24])[N:12]([c:15]3[s:16][c:17]([C:21](=[O:22])[OH:23])[c:18]([CH3:20])[n:19]3)[CH2:13][CH2:14]2)=[O:25])[cH:26][cH:27]1.[NH2:59][CH2:60][c:61]1[cH:62][n:63][cH:64][cH:65][cH:66]1.[OH:28][n:29]1[c:30]2[cH:31][cH:32][cH:33][cH:34][c:35]2[n:36][n:37]1>>[F:1][c:2]1[cH:3][cH:4][c:5]([CH2:6][NH:7][C:8]([CH2:9][N:10]2[C:11](=[O:24])[N:12]([c:15]3[s:16][c:17]([C:21](=[O:23])[NH:59][CH2:60][c:61]4[cH:62][n:63][cH:64][cH:65][cH:66]4)[c:18]([CH3:20])[n:19]3)[CH2:13][CH2:14]2)=[O:25])[cH:26][cH:27]1

Participants

9

Reactant 8

HCID 313Hydrochloric AcidHCID 6228DimethylformamideHCID 8857Ethyl AcetateHCID 159081-Ethyl-3-(3'-dimethylaminopropyl)carbodiimideHCID 310183-PyridinemethanamineHCID 757711-HydroxybenzotriazoleHCID 81531DiisopropylethylamineHCID 579197422-(3-(2-(4-Fluorobenzylamino)-2-oxoethyl)-2-oxoimidazolidin-1-yl)-4-methylthiazole-5-carboxylic acid

Product 1

HCID 579197492-(3-(2-(4-fluorobenzylamino)-2-oxoethyl)-2-oxoimidazolidin-1-yl)-4-methyl-N-(pyridin-3-ylmethyl)thiazole-5-carboxamide

Sources & evidence

ORD record
ord-859a5197c6f24fb9bcf0fa03a197ac4f
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (7/10)

Reaction notes

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