Isonicotinic Acid → N-[6-(3-{[3-(1-cyanocyclopropyl)benzoyl]amino}phenoxy)imidazo[1,2-b]pyridazin-2-yl]isonicotinamide
Reaction equation
[CH3:47][N:48]([CH3:49])[CH:50]=[O:51].[CH3:52][N:53]1[CH2:54][CH2:55][CH2:56][C:57]1=[O:58].[Cl:41][C:42]([C:43]([Cl:44])=[O:45])=[O:46].[NH2:1][c:2]1[n:3][c:4]2[n:5]([n:6][c:7]([O:10][c:11]3[cH:12][c:13]([NH:17][C:18]([c:19]4[cH:20][c:21]([C:25]5([C:28]#[N:29])[CH2:26][CH2:27]5)[cH:22][cH:23][cH:24]4)=[O:30])[cH:14][cH:15][cH:16]3)[cH:8][cH:9]2)[cH:31]1.[O:59]1[CH2:60][CH2:61][CH2:62][CH2:63]1.[OH:32][C:33](=[O:34])[c:35]1[cH:36][cH:37][n:38][cH:39][cH:40]1>>[NH:1]([c:2]1[n:3][c:4]2[n:5]([n:6][c:7]([O:10][c:11]3[cH:12][c:13]([NH:17][C:18]([c:19]4[cH:20][c:21]([C:25]5([C:28]#[N:29])[CH2:26][CH2:27]5)[cH:22][cH:23][cH:24]4)=[O:30])[cH:14][cH:15][cH:16]3)[cH:8][cH:9]2)[cH:31]1)[C:33](=[O:32])[c:35]1[cH:36][cH:37][n:38][cH:39][cH:40]1Participants
7
Reactant 6
Product 1
Sources & evidence
- ORD record
- ord-9b135077b1ec47d0a51c546691caf4f1
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (7/10)
Reaction notes
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