HRID1120285

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID313

Hydrochloric Acid

ClH

HCID3283

Diethyl Ether

C4H10O

HCID3776

Isopropanol

C3H8O

HCID6228

N,N-Dimethylformamide

C3H7NO

HCID6344

Dichloromethane

CH2Cl2

HCID13838

Hexamethyldisilazane

C6H19NSi2

HCID5360545

Sodium

HCID11823941

4-chloro-6-methoxy-7-(3-morpholin-4-ylpropoxy)quinazoline

C16H20ClN3O3

HCID22140793

6-Chloro-1-benzofuran-7-amine

C8H6ClNO

PRODUCTS

生成物

结构：COc1cc2c(Nc3c(Cl)ccc4ccoc34)ncnc2cc1OCCCN1CCOCC1

HCID5330180

未命名化合物

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-4e88380462b647d18610815bbb43bf33
来源数据集: Training data from https://doi.org/10.1039/C8SC04228D (7/10)
DOI: 10.1039/C8SC04228D
来源说明: Training data from https://doi.org/10.1039/C8SC04228D (7/10)

反应 SMILES

[CH2:51]([Cl:52])[Cl:53].[CH3:2][Si:3]([CH3:4])([CH3:5])[NH:6][Si:7]([CH3:8])([CH3:9])[CH3:10].[CH3:58][CH2:59][O:60][CH2:61][CH3:62].[CH:54]([OH:55])([CH3:56])[CH3:57].[Cl:22][c:23]1[n:24][cH:25][n:26][c:27]2[cH:28][c:29]([O:35][CH2:36][CH2:37][CH2:38][N:39]3[CH2:40][CH2:41][O:42][CH2:43][CH2:44]3)[c:30]([O:33][CH3:34])[cH:31][c:32]12.[ClH:45].[NH2:11][c:12]1[c:13]([Cl:21])[cH:14][cH:15][c:16]2[cH:17][cH:18][o:19][c:20]12.[Na:1].[O:46]=[CH:47][N:48]([CH3:49])[CH3:50]>>[NH:11]([c:12]1[c:13]([Cl:21])[cH:14][cH:15][c:16]2[cH:17][cH:18][o:19][c:20]12)[c:23]1[n:24][cH:25][n:26][c:27]2[cH:28][c:29]([O:35][CH2:36][CH2:37][CH2:38][N:39]3[CH2:40][CH2:41][O:42][CH2:43][CH2:44]3)[c:30]([O:33][CH3:34])[cH:31][c:32]12