Tetrahydrofuran → HCID 67050111, compound

HRID 1121454Notes

Reaction equation

HRID 1121454 reaction equation
[Br:1][c:2]1[c:3](-[c:9]2[n:10][c:11]3[c:12]([n:13]2[CH2:14][CH:15]2[CH2:16][CH2:17][CH2:18][CH2:19][CH2:20]2)[cH:21][cH:22][cH:23][cH:24]3)[cH:4][cH:5][c:6]([Cl:8])[cH:7]1.[C:25](#[CH:26])[c:27]1[cH:28][cH:29][c:30]([C:31]#[N:32])[cH:33][cH:34]1.[CH2:35]([N:36]([CH2:37][CH3:38])[CH2:39][CH3:40])[CH3:41].[Cu:88][I:89].[O:42]1[CH2:43][CH2:44][CH2:45][CH2:46]1.[Pd:47]([Cl:48])[Cl:49].[c:50]1([P:51]([c:52]2[cH:53][cH:54][cH:55][cH:56][cH:57]2)[c:58]2[cH:59][cH:60][cH:61][cH:62][cH:63]2)[cH:64][cH:65][cH:66][cH:67][cH:68]1.[c:69]1([P:70]([c:71]2[cH:72][cH:73][cH:74][cH:75][cH:76]2)[c:77]2[cH:78][cH:79][cH:80][cH:81][cH:82]2)[cH:83][cH:84][cH:85][cH:86][cH:87]1>>[c:2]1([C:26]#[C:25][c:27]2[cH:28][cH:29][c:30]([C:31]#[N:32])[cH:33][cH:34]2)[c:3](-[c:9]2[n:10][c:11]3[c:12]([n:13]2[CH2:14][CH:15]2[CH2:16][CH2:17][CH2:18][CH2:19][CH2:20]2)[cH:21][cH:22][cH:23][cH:24]3)[cH:4][cH:5][c:6]([Cl:8])[cH:7]1

Participants

8

Reactant 7

HCID 8028TetrahydrofuranHCID 8471TriethylamineHCID 11776Triphenylphosphine2×HCID 24290Palladium ChlorideHCID 24350Copper(1+) iodide; Copper(I) iodide; Cuprous iodide; Cuprous iodide (CuI)HCID 45472454-EthynylbenzonitrileHCID 67049683HCID 67049683, compound

Product 1

HCID 67050111HCID 67050111, compound

Sources & evidence

ORD record
ord-f4265624bb654f2cbf7aa8dbb37b7cf4
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (7/10)

Reaction notes

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