Ammonium → 5-methoxy-1H-pyrrolo[2,3-b]pyridine
Reaction equation
[Br:1][c:2]1[cH:3][c:4]2[c:5]([n:6][cH:7]1)[nH:8][cH:9][cH:10]2.[CH3:11][O-:12].[CH3:19][N:20]([CH3:21])[CH:22]=[O:23].[CH3:24][OH:25].[CH3:26][CH2:27][O:28][C:29](=[O:30])[CH3:31].[Cl-:17].[Cu:32][I:33].[Cu:34][Br:35].[NH4+:16].[NH4+:18].[Na+:13].[OH-:15].[OH2:14]>>[c:2]1([O:12][CH3:11])[cH:3][c:4]2[c:5]([n:6][cH:7]1)[nH:8][cH:9][cH:10]2Participants
13
Reactant 12
HCID 223Ammonium2×
HCID 312Chloride
HCID 887Methanol
HCID 923Sodium ion
HCID 961Hydroxide
HCID 962Water
HCID 6228Dimethylformamide
HCID 8857Ethyl Acetate
HCID 24350Copper(1+) iodide; Copper(I) iodide; Cuprous iodide; Cuprous iodide (CuI)
HCID 24593copper(I) bromide
HCID 3826051Methoxide
HCID 103079325-bromo-1H-pyrrolo[2,3-b]pyridineProduct 1
Sources & evidence
- ORD record
- ord-5aaa7dc1ba1e4a7ba0d0fd36be7aefe9
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (7/10)
Reaction notes
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