Hydrochloric Acid → Ethyl-1-benzoyl-4-(phenylmethyl)-4-piperidinecarboxylate

HRID 119767Notes

Reaction equation

HRID 119767 reaction equation
[Br:30][CH2:31][c:32]1[cH:33][cH:34][cH:35][cH:36][cH:37]1.[C:11]([c:12]1[cH:13][cH:14][cH:15][cH:16][cH:17]1)(=[O:18])[N:19]1[CH2:20][CH2:21][CH:22]([C:25](=[O:26])[O:27][CH2:28][CH3:29])[CH2:23][CH2:24]1.[CH3:1][Si:2]([N-:3][Si:4]([CH3:5])([CH3:6])[CH3:7])([CH3:8])[CH3:9].[CH3:44][CH2:45][O:46][C:47](=[O:48])[CH3:49].[ClH:43].[Li+:10].[O:38]1[CH2:39][CH2:40][CH2:41][CH2:42]1>>[C:11]([c:12]1[cH:13][cH:14][cH:15][cH:16][cH:17]1)(=[O:18])[N:19]1[CH2:20][CH2:21][C:22]([C:25](=[O:26])[O:27][CH2:28][CH3:29])([CH2:31][c:32]2[cH:33][cH:34][cH:35][cH:36][cH:37]2)[CH2:23][CH2:24]1

Participants

8

Reactant 7

HCID 313Hydrochloric AcidHCID 7498Benzyl BromideHCID 8028TetrahydrofuranHCID 8857Ethyl AcetateHCID 28486Lithium ionHCID 735824Ethyl 1-benzoylpiperidine-4-carboxylateHCID 3280088Npc316347

Product 1

HCID 10545888Ethyl-1-benzoyl-4-(phenylmethyl)-4-piperidinecarboxylate

Sources & evidence

ORD record
ord-559fd547c26e4b2987473e2ee2b34cf8
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (2/10)

Reaction notes

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