2-Aminothiazole → HCID 15604848, compound

HRID 1240131Notes

Reaction equation

HRID 1240131 reaction equation
[CH2:40]1[O:41][CH2:42][CH2:43][CH2:44]1.[CH2:53]1[O:54][CH2:55][CH2:56][CH2:57]1.[CH3:1][C:2]1([CH3:19])[CH2:3][NH:4][C:5](=[O:18])[c:6]2[n:7]1[c:8]1[cH:9][c:10]([C:15](=[O:16])[OH:17])[cH:11][cH:12][c:13]1[cH:14]2.[Cl:20][C:21]([C:22]([Cl:23])=[O:24])=[O:25].[Cl:50][CH2:51][Cl:52].[NH2:26][c:27]1[s:28][cH:29][cH:30][n:31]1.[O:45]=[CH:46][N:47]([CH3:48])[CH3:49].[n:32]1[c:33]([CH3:34])[cH:35][cH:36][cH:37][c:38]1[CH3:39]>>[CH3:1][C:2]1([CH3:19])[CH2:3][NH:4][C:5](=[O:18])[c:6]2[n:7]1[c:8]1[cH:9][c:10]([C:15](=[O:16])[NH:26][c:27]3[s:28][cH:29][cH:30][n:31]3)[cH:11][cH:12][c:13]1[cH:14]2

Participants

8

Reactant 7

HCID 21552-AminothiazoleHCID 6228DimethylformamideHCID 6344DichloromethaneHCID 79372,6-LutidineHCID 8028Tetrahydrofuran2×HCID 65578Oxalyl chlorideHCID 58767565HCID 58767565, compound

Product 1

HCID 15604848HCID 15604848, compound

Sources & evidence

ORD record
ord-f241623237e14dd6b5062419096ea51f
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (5/10)

Reaction notes

Loading…