1,2-Dichloroethane → methyl 6-bromo-1-cyclopropyl-1H-indole-4-carboxylate

HRID 1240920Notes

Reaction equation

HRID 1240920 reaction equation
[Br:1][c:2]1[cH:3][c:4]([C:11](=[O:12])[O:13][CH3:14])[c:5]2[cH:6][cH:7][nH:8][c:9]2[cH:10]1.[C:45]([O-:46])(=[O:47])[CH3:48].[C:50]([O-:51])(=[O:52])[CH3:53].[CH3:54][CH2:55][O:56][C:57](=[O:58])[CH3:59].[CH:15]1([B:18]([OH:19])[OH:20])[CH2:16][CH2:17]1.[Cl-:39].[Cl:41][CH2:42][CH2:43][Cl:44].[Cu+2:49].[NH4+:40].[Na+:21].[Na+:22].[O-:23][C:24](=[O:25])[O-:26].[OH2:60].[n:27]1[cH:28][cH:29][cH:30][cH:31][c:32]1-[c:33]1[cH:34][cH:35][cH:36][cH:37][n:38]1>>[Br:1][c:2]1[cH:3][c:4]([C:11](=[O:12])[O:13][CH3:14])[c:5]2[cH:6][cH:7][n:8]([CH:15]3[CH2:16][CH2:17]3)[c:9]2[cH:10]1

Participants

13

Reactant 12

HCID 111,2-DichloroethaneHCID 175Acetate2×HCID 223AmmoniumHCID 312ChlorideHCID 923Sodium ion2×HCID 962WaterHCID 14742,2'-BipyridineHCID 8857Ethyl AcetateHCID 19660Carbonate IonHCID 27099Cupric cationHCID 2760897Cyclopropylboronic acidHCID 13770009methyl 6-bromo-1H-indole-4-carboxylate

Product 1

HCID 67467490methyl 6-bromo-1-cyclopropyl-1H-indole-4-carboxylate

Sources & evidence

ORD record
ord-e6a624a585bd4451b771e9a35ab7899b
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (5/10)

Reaction notes

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