Dimethylformamide → Phthalimide

HRID 125582Notes

Reaction equation

HRID 125582 reaction equation
[CH2:31]1[CH2:32][CH2:33][C:34]2=[N:39][CH2:38][CH2:37][CH2:36][N:35]2[CH2:40][CH2:41]1.[CH3:24][CH2:25][N:26]([CH2:27][CH3:28])[CH2:29][CH3:30].[F:1][c:2]1[c:3]([F:4])[c:5]([CH3:6])[cH:7][cH:8][c:9]1[CH2:10][Br:11].[O:42]=[CH:43][N:44]([CH3:45])[CH3:46].[OH:12][N:13]1[C:14](=[O:23])[c:15]2[c:16]([cH:19][cH:20][cH:21][cH:22]2)[C:17]1=[O:18]>>[NH:13]1[C:14](=[O:23])[c:15]2[c:16]([cH:19][cH:20][cH:21][cH:22]2)[C:17]1=[O:18]

Participants

6

Reactant 5

HCID 6228DimethylformamideHCID 8471TriethylamineHCID 10665N-HydroxyphthalimideHCID 811841,8-Diazabicyclo(5.4.0)undec-7-eneHCID 27741491-(Bromomethyl)-2,3-difluoro-4-methylbenzene

Product 1

HCID 6809Phthalimide

Sources & evidence

ORD record
ord-a1247869ea7c41dd99d51b8e0abafe41
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (2/10)

Reaction notes

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