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HRID132833

反应详情

EQUATION

反应方程式

HRID 132833 的结构方程式

REACTANTS

反应物

5
结构：O=C(O)C(F)(F)F
HCID6422

未命名化合物

结构：C1CCNCC1
HCID8082

Piperidine

C5H11N

结构：On1nnc2ccccc21
HCID75771

1-Hydroxybenzotriazole

C6H5N3O

结构：CCN(C(C)C)C(C)C
HCID81531

Diisopropylethylamine

C8H19N

结构：CC(C)(C)OC(=O)N1Cc2ccccc2C[C@H]1C(=O)O
HCID664088

未命名化合物

PRODUCTS

生成物

1
结构：O=C([C@@H]1Cc2ccccc2CN1)N1CCCCC1
HCID10657955

未命名化合物

AUXILIARIES

试剂、催化剂与溶剂

1
结构：ClCCCl
溶剂HCID11

1,2-Dichloroethane

C2H4Cl2

PROCEDURE

实验过程

Following a procedure similar to that described for Intermediate 14, treatment of Boc-TIC-OH with EDC, HOBt, N,N-diisopropylethylamine and piperidine, followed by deprotection using trifluoroacetic acid, afforded the title compound as a white foam. LC/MS: 245.2 (M+1).