Dimethylformamide → 4-(7-Hydroxy-6-((trimethylsilyl)ethynyl)quinazolin-2-ylamino)-N-isopropylbenzamide
Reaction equation
[Br:1][c:2]1[cH:3][c:4]2[cH:5][n:6][c:7]([NH:13][c:14]3[cH:15][cH:16][c:17]([C:18](=[O:19])[NH:20][CH:21]([CH3:22])[CH3:23])[cH:24][cH:25]3)[n:8][c:9]2[cH:10][c:11]1[OH:12].[CH3:26][CH2:27][N:28]([CH2:29][CH3:30])[CH2:31][CH3:32].[CH3:33][Si:34]([CH3:35])([CH3:36])[C:37]#[CH:38].[CH3:44][CH2:45][O:46][C:47](=[O:48])[CH3:49].[Cu:50][I:51].[O:39]=[CH:40][N:41]([CH3:42])[CH3:43]>>[c:2]1([C:38]#[C:37][Si:34]([CH3:33])([CH3:35])[CH3:36])[cH:3][c:4]2[cH:5][n:6][c:7]([NH:13][c:14]3[cH:15][cH:16][c:17]([C:18](=[O:19])[NH:20][CH:21]([CH3:22])[CH3:23])[cH:24][cH:25]3)[n:8][c:9]2[cH:10][c:11]1[OH:12]Participants
7
Reactant 6
Product 1
Sources & evidence
- ORD record
- ord-50c80eb199f44d3b96fda92d7ea4863e
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (1/10)
Reaction notes
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