Hydrochloric Acid → 2-(Azetidin-1-ylcarbonyl)-7-chlorothieno[3,2-b]pyridine

HRID 1541363Notes

Reaction equation

HRID 1541363 reaction equation
[CH2:35]([Cl:36])[Cl:37].[CH:26]([N:27]([CH2:28][CH3:29])[CH:30]([CH3:31])[CH3:32])([CH3:33])[CH3:34].[Cl:15][C:16]([C:17]([Cl:18])=[O:19])=[O:20].[Cl:1][c:2]1[c:3]2[c:4]([n:5][cH:6][cH:7]1)[cH:8][c:9]([C:11](=[O:12])[O-:13])[s:10]2.[ClH:21].[Li+:14].[NH:22]1[CH2:23][CH2:24][CH2:25]1.[O:38]=[CH:39][N:40]([CH3:41])[CH3:42]>>[Cl:1][c:2]1[c:3]2[c:4]([n:5][cH:6][cH:7]1)[cH:8][c:9]([C:11](=[O:13])[N:22]1[CH2:23][CH2:24][CH2:25]1)[s:10]2

Participants

9

Reactant 8

HCID 313Hydrochloric AcidHCID 6228DimethylformamideHCID 6344DichloromethaneHCID 10422AzetidineHCID 28486Lithium ionHCID 65578Oxalyl chlorideHCID 81531DiisopropylethylamineHCID 178524058HCID 178524058, compound

Product 1

HCID 221435492-(Azetidin-1-ylcarbonyl)-7-chlorothieno[3,2-b]pyridine

Sources & evidence

ORD record
ord-b4ef16f5ab42464b9906a91ac6c9ad60
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (1/10)

Reaction notes

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