Hydrochloric Acid → tert-butyl N-[1-[2-[2-(benzenesulfonamido)phenyl]ethyl-methylamino]-3-naphthalen-2-yl-1-oxopropan-2-yl]-N-methylcarbamate

HRID 1546421Notes

Reaction equation

HRID 1546421 reaction equation
[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[N:8]([CH3:9])[CH:10]([C:11](=[O:12])[OH:13])[CH2:14][c:15]1[cH:16][c:17]2[cH:18][cH:19][cH:20][cH:21][c:22]2[cH:23][cH:24]1.[CH2:67]([N:68]([CH:69]([CH3:70])[CH3:71])[CH:72]([CH3:73])[CH3:74])[CH3:75].[CH3:36][N:37]([CH3:38])[CH2:39][CH2:40][CH2:41][N:42]=[C:43]=[N:44][CH2:45][CH3:46].[CH3:47][NH:48][CH2:49][CH2:50][c:51]1[c:52]([NH:57][S:58](=[O:59])(=[O:60])[c:61]2[cH:62][cH:63][cH:64][cH:65][cH:66]2)[cH:53][cH:54][cH:55][cH:56]1.[CH3:79][N:80]([CH3:81])[CH:82]=[O:83].[CH3:84][CH2:85][O:86][C:87](=[O:88])[CH3:89].[Cl:76][CH2:77][Cl:78].[ClH:35].[OH:25][n:26]1[c:27]2[n:28][cH:29][cH:30][cH:31][c:32]2[n:33][n:34]1>>[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[N:8]([CH3:9])[CH:10]([C:11](=[O:13])[N:48]([CH3:47])[CH2:49][CH2:50][c:51]1[c:52]([NH:57][S:58](=[O:59])(=[O:60])[c:61]2[cH:62][cH:63][cH:64][cH:65][cH:66]2)[cH:53][cH:54][cH:55][cH:56]1)[CH2:14][c:15]1[cH:16][c:17]2[cH:18][cH:19][cH:20][cH:21][c:22]2[cH:23][cH:24]1

Participants

10

Reactant 9

HCID 313Hydrochloric AcidHCID 6228DimethylformamideHCID 6344DichloromethaneHCID 8857Ethyl AcetateHCID 159081-Ethyl-3-(3'-dimethylaminopropyl)carbodiimideHCID 81531DiisopropylethylamineHCID 181649HOAtHCID 10732262N-[2-(2-(methylamino)ethyl)phenyl]benzenesulfonamideHCID 223269722-[Methyl-[(2-methylpropan-2-yl)oxycarbonyl]amino]-3-naphthalen-2-ylpropanoic acid

Product 1

HCID 20677512tert-butyl N-[1-[2-[2-(benzenesulfonamido)phenyl]ethyl-methylamino]-3-naphthalen-2-yl-1-oxopropan-2-yl]-N-methylcarbamate

Sources & evidence

ORD record
ord-ac8b00b9f28e422e9363132093b044a2
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (1/10)

Reaction notes

Loading…