Ammonium → 2,8-Dichloro-7-methoxy-4-(4-methoxy-benzyloxy)-quinoline

HRID 1554069Notes

Reaction equation

HRID 1554069 reaction equation
[CH2:13]1[O:14][CH2:15][CH2:16][O:17][CH2:18][CH2:19][O:20][CH2:21][CH2:22][O:23][CH2:24][CH2:25][O:26][CH2:27]1.[CH3:3][O:4][c:5]1[cH:6][cH:7][c:8]([CH2:9][OH:10])[cH:11][cH:12]1.[CH3:50][CH2:51][O:52][C:53](=[O:54])[CH3:55].[Cl-:43].[Cl:28][c:29]1[n:30][c:31]2[c:32]([Cl:42])[c:33]([O:40][CH3:41])[cH:34][cH:35][c:36]2[c:37]([Cl:39])[cH:38]1.[H-:1].[NH4+:44].[Na+:2].[O:45]=[CH:46][N:47]([CH3:48])[CH3:49].[OH2:56]>>[CH3:3][O:4][c:5]1[cH:6][cH:7][c:8]([CH2:9][O:10][c:37]2[c:36]3[c:31]([n:30][c:29]([Cl:28])[cH:38]2)[c:32]([Cl:42])[c:33]([O:40][CH3:41])[cH:34][cH:35]3)[cH:11][cH:12]1

Participants

11

Reactant 10

HCID 223AmmoniumHCID 312ChlorideHCID 923Sodium ionHCID 962WaterHCID 6228DimethylformamideHCID 77384-Methoxybenzyl alcoholHCID 8857Ethyl AcetateHCID 3633615-Crown-5HCID 166653HydrideHCID 27945162,4,8-Trichloro-7-methoxyquinoline

Product 1

HCID 566051532,8-Dichloro-7-methoxy-4-(4-methoxy-benzyloxy)-quinoline

Sources & evidence

ORD record
ord-1f47159fa7984508a4460143eb7238f5
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (1/10)

Reaction notes

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