Tetrahydrofuran → 3-(4-[1,2,3]Triazol-1-yl-but-1-ynyl)-6-{2-[2-(4-trifluoromethyl-phenyl)-vinyl]-oxazol-4-ylmethoxy}-pyridazine
Reaction equation
[CH2:27]([CH2:28][C:29]#[CH:30])[n:31]1[n:32][n:33][cH:34][cH:35]1.[CH2:36]([N:37]([CH2:38][CH3:39])[CH2:40][CH3:41])[CH3:42].[CH2:49]1[O:50][CH2:51][CH2:52][CH2:53]1.[CH3:43][CH2:44][O:45][C:46](=[O:47])[CH3:48].[Cu:54]([I:55])[I:56].[I:1][c:2]1[n:3][n:4][c:5]([O:8][CH2:9][c:10]2[n:11][c:12]([CH:15]=[CH:16][c:17]3[cH:18][cH:19][c:20]([C:23]([F:24])([F:25])[F:26])[cH:21][cH:22]3)[o:13][cH:14]2)[cH:6][cH:7]1.[Pd:57]([Cl:58])[Cl:59].[c:60]1([P:61]([c:62]2[cH:63][cH:64][cH:65][cH:66][cH:67]2)[c:68]2[cH:69][cH:70][cH:71][cH:72][cH:73]2)[cH:74][cH:75][cH:76][cH:77][cH:78]1.[c:79]1([P:80]([c:81]2[cH:82][cH:83][cH:84][cH:85][cH:86]2)[c:87]2[cH:88][cH:89][cH:90][cH:91][cH:92]2)[cH:93][cH:94][cH:95][cH:96][cH:97]1>>[c:2]1([C:30]#[C:29][CH2:28][CH2:27][n:31]2[n:32][n:33][cH:34][cH:35]2)[n:3][n:4][c:5]([O:8][CH2:9][c:10]2[n:11][c:12]([CH:15]=[CH:16][c:17]3[cH:18][cH:19][c:20]([C:23]([F:24])([F:25])[F:26])[cH:21][cH:22]3)[o:13][cH:14]2)[cH:6][cH:7]1Participants
9
Reactant 8
Product 1
Sources & evidence
- ORD record
- ord-8900bee7deb041f2be40b91ded2afba8
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (1/10)
Reaction notes
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