HRID1571389

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID2155

2-Aminothiazole

C3H4N2S

HCID6228

Dimethylformamide

C3H7NO

HCID6344

Dichloromethane

CH2Cl2

HCID8028

Tetrahydrofuran

C4H8O

HCID65578

Ethanedioyl dichloride

C2Cl2O2

HCID81531

Diisopropylethylamine

C8H19N

HCID22315323

未命名化合物

PRODUCTS

产物

反应SMILES：COc1ccc(C(CC2CCCC2)C(=O)Nc2nccs2)cc1F

HCID22315179

未命名化合物

来源与证据

来源类型: Open Reaction Database
ORD记录: ord-3823f0197c5648458392056957775e6e
来源数据集: Training data from https://doi.org/10.1039/C8SC04228D (1/10)
DOI: 10.1039/C8SC04228D
来源说明: Training data from https://doi.org/10.1039/C8SC04228D (1/10)

反应SMILES

[CH2:41]([Cl:42])[Cl:43].[CH3:49][N:50]([CH3:51])[CH:52]=[O:53].[CH:1]1([CH2:6][CH:7]([C:8](=[O:9])[OH:10])[c:11]2[cH:12][c:13]([F:19])[c:14]([O:17][CH3:18])[cH:15][cH:16]2)[CH2:2][CH2:3][CH2:4][CH2:5]1.[CH:32]([N:33]([CH2:34][CH3:35])[CH:36]([CH3:37])[CH3:38])([CH3:39])[CH3:40].[Cl:20][C:21]([C:22]([Cl:23])=[O:24])=[O:25].[NH2:26][c:27]1[s:28][cH:29][cH:30][n:31]1.[O:44]1[CH2:45][CH2:46][CH2:47][CH2:48]1>>[CH:1]1([CH2:6][CH:7]([C:8](=[O:10])[NH:26][c:27]2[s:28][cH:29][cH:30][n:31]2)[c:11]2[cH:12][c:13]([F:19])[c:14]([O:17][CH3:18])[cH:15][cH:16]2)[CH2:2][CH2:3][CH2:4][CH2:5]1