Pyridine → HCID 57897304, compound

HRID 1574930Notes

Reaction equation

HRID 1574930 reaction equation
[Br:1][c:2]1[c:3]([N:12]2[CH2:13][CH2:14][N:15]([CH:18]([c:19]3[cH:20][cH:21][cH:22][cH:23][n:24]3)[CH3:25])[CH2:16][CH2:17]2)[c:4]([N+:9](=[O:10])[O-:11])[c:5]([NH2:8])[n:6][cH:7]1.[Br:57][c:58]1[c:59]([Cl:60])[c:61]([N+:62]([O-:63])=[O:64])[c:65]([NH2:66])[n:67][cH:68]1.[Br:75][c:76]1[cH:77][cH:78][cH:79][cH:80][n:81]1.[CH2:69]1[NH:70][CH2:71][CH2:72][NH:73][CH2:74]1.[CH:82]([OH:83])([CH3:84])[CH3:85].[CH:86]([N:87]([CH2:88][CH3:89])[CH:90]([CH3:91])[CH3:92])([CH3:93])[CH3:94].[Cl:101][CH2:102][Cl:103].[F:26][C:27]([c:28]1[cH:29][cH:30][c:31]([CH2:34][N:35]2[CH2:36][CH2:37][N:38]([C:39]([O:40][C:41]([CH3:42])([CH3:43])[CH3:44])=[O:45])[CH2:46][CH2:47]2)[cH:32][n:33]1)([F:48])[F:49].[F:50][C:51]([F:52])([F:53])[C:54]([OH:55])=[O:56].[cH:95]1[cH:96][cH:97][n:98][cH:99][cH:100]1>>[Br:1][c:2]1[c:3]([N:12]2[CH2:13][CH2:14][N:15]([CH2:18][c:31]3[cH:30][cH:29][c:28]([C:27]([F:26])([F:48])[F:49])[n:33][cH:32]3)[CH2:16][CH2:17]2)[c:4]([N+:9](=[O:10])[O-:11])[c:5]([NH2:8])[n:6][cH:7]1

Participants

11

Reactant 10

HCID 1049PyridineHCID 3776IsopropanolHCID 4837PiperazineHCID 6344DichloromethaneHCID 6422Trifluoroacetic acidHCID 79732-BromopyridineHCID 81531DiisopropylethylamineHCID 454802365-Bromo-4-chloro-3-nitropyridin-2-amineHCID 578971485-Bromo-3-nitro-4-(4-(1-(pyridin-2-yl)ethyl)piperazin-1-yl)pyridin-2-amineHCID 57897218HCID 57897218, compound

Product 1

HCID 57897304HCID 57897304, compound

Sources & evidence

ORD record
ord-ae90e344cf2f4a0994b57f91c1958a82
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (1/10)

Reaction notes

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