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HRID1676935

反应详情

EQUATION

反应方程式

HRID 1676935 的结构方程式

REACTANTS

反应物

4
结构：NS(=O)(=O)c1cc(-c2nn[nH]n2)c(NCc2cccs2)cc1Cl
HCID2273

Azosemide

C12H11ClN6O2S2

结构：[I-].[Na+]
HCID5238

Sodium Iodide

INa

结构：CCN(CC)CC
HCID8471

Triethylamine

C6H15N

结构：CC(C)(C)C(=O)OCCl
HCID87885

Propanoic acid, 2,2-dimethyl-, chloromethyl ester

C6H11ClO2

PRODUCTS

生成物

1
结构：CC(C)(C)C(=O)OCn1nnnc1-c1cc(S(N)(=O)=O)c(Cl)cc1NCc1cccs1
HCID60208421

未命名化合物

AUXILIARIES

试剂、催化剂与溶剂

1
结构：CN(C)C=O
溶剂HCID6228

N,N-Dimethylformamide

C3H7NO

PROCEDURE

实验过程

In a similar manner to Example 12, azosemide can be reacted with chloromethyl pivalate, triethylamine and sodium iodide in DMF to yield 5-[1-(t-Butylcarbonyloxymethyl)-1H-tetrazol-5-yl]-2-chloro-4-[(2-thienylmethyl)amino]benzenesulfonamide.