Hydrochloric Acid → Sodium 4-chlorophenolate

HRID 1733544Notes

Reaction equation

HRID 1733544 reaction equation
[Cl:1][C:2]1[CH:7]=[CH:6][C:5]([OH:8])=[CH:4][CH:3]=1.[H-].[Na+:10].Cl>C1COCC1>[Cl:1][C:2]1[CH:7]=[CH:6][C:5]([O-:8])=[CH:4][CH:3]=1.[Na+:10]

Participants

5

Reactant 3

HCID 313Hydrochloric AcidHCID 46844-Chlorophenol2×HCID 24758Sodium hydride

Product 1

HCID 23666363Sodium 4-chlorophenolate

Reagents, catalysts & solvents 1

HCID 8028TetrahydrofuranSolvent

Procedure

A large batch of sodium p-chlorophenoxide salt was prepared by the reaction of 529.4 grams (4.12 moles) of p-chlorophenol with 99.0 grams (4.12 moles) of sodium hydride in THF at room temperature. A light yellow solution was obtained after 2 hours. A sample of the salt was neutralized with HCl and analyzed. The analysis showed 100% p-chlorophenol.

Workup

  1. customA light yellow solution was obtained after 2 hours

Sources & evidence

ORD record
ord-b6a20a2320bd4858b19b7c49fa3ded6f
Source dataset
uspto-grants-1980_12
Patent number
US04242493

Reaction notes

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