Carbon Monoxide → Methyl 3-oxocyclopent-1-enecarboxylate

HRID 2002410Notes

Reaction equation

HRID 2002410 reaction equation
[C-:1]#[O+:2].[CH3:3]c1ccc(S([O:4][C:5]([CH2:10][CH2:9][C:7]2=[O:8])=[CH:6]2)(=O)=O)cc1>>[CH3:3][O:4][C:1]([C:5]([CH2:10][CH2:9][C:7]1=[O:8])=[CH:6]1)=[O:2]

Participants

9

Reactant 3

HCID 281Carbon MonoxideHCID 887MethanolHCID 86196686(3-Oxocyclopenten-1-yl) 4-methylbenzenesulfonate

Product 1

HCID 11029917Methyl 3-oxocyclopent-1-enecarboxylate

Reagents, catalysts & solvents 5

HCID 81531DiisopropylethylamineReagentHCID 167845palladium(II) acetateCatalystHCID 611933(Pentane-1,5-diyl)bis(di-tert-butylphosphane)CatalystHCID 8028TetrahydrofuranSolventHCID 117669-PhenylanthraceneInternal standard

Conditions

Temperature
110 °C

Sources & evidence

ORD record
ord-349e1cdea0a744c3913db1d513da1a7c
Source dataset
39k HTE dataset from Pfizer
Original link
View source

Reaction notes

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