1,4-Dimethyl-1H-1,2,3-triazole → HCID 178425080, compound

HRID 2018160Notes

Reaction equation

HRID 2018160 reaction equation
[CH3:1][c:2]1[n:7][n:6][n:4]([CH3:5])[cH:3]1.[CH3:8][c:9]1[n:36][c:27]([O:28][CH2:29][c:30]2[cH:35][cH:34][cH:33][cH:32][cH:31]2)[c:13]([CH2:14][N:15]3[C:25](=[O:26])[c:24]([c:18]4[CH2:17][CH2:16]3)[c:22]([Cl:23])[c:21](OS(C(F)(F)F)(=O)=O)[cH:20][cH:19]4)[c:11]([CH3:12])[cH:10]1>>[CH3:8][c:9]1[n:36][c:27]([O:28][CH2:29][c:30]2[cH:35][cH:34][cH:33][cH:32][cH:31]2)[c:13]([CH2:14][N:15]3[C:25](=[O:26])[c:24]([c:18]4[CH2:17][CH2:16]3)[c:22]([Cl:23])[c:21]([c:3]5[n:4]([CH3:5])[n:6][n:7][c:2]5[CH3:1])[cH:20][cH:19]4)[c:11]([CH3:12])[cH:10]1

Participants

8

Reactant 2

HCID 152571421,4-Dimethyl-1H-1,2,3-triazoleHCID 178425082HCID 178425082, compound

Product 1

HCID 178425080HCID 178425080, compound

Reagents, catalysts & solvents 5

HCID 517044Potassium AcetateReagentHCID 75806TricyclohexylphosphineCatalystHCID 167845palladium(II) acetateCatalystHCID 8028TetrahydrofuranSolventHCID 117669-PhenylanthraceneInternal standard

Conditions

Temperature
120 °C

Sources & evidence

ORD record
ord-5b7c7c4aecd84fa7a73fe05c15c6d31f
Source dataset
39k HTE dataset from Pfizer
Original link
View source

Reaction notes

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