Hydrochloric Acid → tert-butyl N-[3-(4-fluorophenyl)-1-(4-hydroxypiperidin-1-yl)-1-oxopropan-2-yl]carbamate
Reaction equation
[C:1](=[O:2])([O:3][C:4]([CH3:5])([CH3:6])[CH3:7])[NH:8][CH:9]([CH2:10][c:11]1[cH:12][cH:13][c:14]([F:17])[cH:15][cH:16]1)[C:18](=[O:19])[OH:20].[CH3:48][CH2:49][N:50]=[C:51]=[N:52][CH2:53][CH2:54][CH2:55][N:56]([CH3:57])[CH3:58].[CH:39]([N:40]([CH2:41][CH3:42])[CH:43]([CH3:44])[CH3:45])([CH3:46])[CH3:47].[ClH:21].[O:59]=[CH:60][N:61]([CH3:62])[CH3:63].[OH:22][CH:23]1[CH2:24][CH2:25][NH:26][CH2:27][CH2:28]1.[OH:29][n:30]1[c:31]2[c:32]([cH:33][cH:34][cH:35][cH:36]2)[n:37][n:38]1>>[C:1](=[O:2])([O:3][C:4]([CH3:5])([CH3:6])[CH3:7])[NH:8][CH:9]([CH2:10][c:11]1[cH:12][cH:13][c:14]([F:17])[cH:15][cH:16]1)[C:18](=[O:20])[N:26]1[CH2:25][CH2:24][CH:23]([OH:22])[CH2:28][CH2:27]1Participants
8
Reactant 7
Product 1
Sources & evidence
- ORD record
- ord-0ca3eebe0fdd4a89b5201c05acc2ac22
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (4/10)
Reaction notes
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