Tetrahydrofuran → HCID 25258327, compound

HRID 2146536Notes

Reaction equation

HRID 2146536 reaction equation
[Br:1][c:2]1[c:3]([NH:12][C:13](=[O:14])[O:15][C:16]([CH3:17])([CH3:18])[CH3:19])[cH:4][c:5]([C:7](=[O:8])[O:9][CH2:10][CH3:11])[s:6]1.[CH2:33]1[O:34][CH2:35][CH2:36][CH2:37]1.[CH3:20][Si:21]([CH3:22])([CH3:23])[C:24]#[CH:25].[CH3:26][CH2:27][N:28]([CH2:29][CH3:30])[CH2:31][CH3:32].[Cu:38][I:39].[Pd:40]([Cl:41])[Cl:42].[c:43]1([P:44]([c:45]2[cH:46][cH:47][cH:48][cH:49][cH:50]2)[c:51]2[cH:52][cH:53][cH:54][cH:55][cH:56]2)[cH:57][cH:58][cH:59][cH:60][cH:61]1.[c:62]1([P:63]([c:64]2[cH:65][cH:66][cH:67][cH:68][cH:69]2)[c:70]2[cH:71][cH:72][cH:73][cH:74][cH:75]2)[cH:76][cH:77][cH:78][cH:79][cH:80]1>>[c:2]1([C:25]#[C:24][Si:21]([CH3:20])([CH3:22])[CH3:23])[c:3]([NH:12][C:13](=[O:14])[O:15][C:16]([CH3:17])([CH3:18])[CH3:19])[cH:4][c:5]([C:7](=[O:8])[O:9][CH2:10][CH3:11])[s:6]1

Participants

8

Reactant 7

HCID 8028TetrahydrofuranHCID 8471TriethylamineHCID 11776Triphenylphosphine2×HCID 24290Palladium ChlorideHCID 24350Copper(1+) iodide; Copper(I) iodide; Cuprous iodide; Cuprous iodide (CuI)HCID 66111TrimethylsilylacetyleneHCID 25258089HCID 25258089, compound

Product 1

HCID 25258327HCID 25258327, compound

Sources & evidence

ORD record
ord-001e5ee25f224f609c52b33aecfab575
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (4/10)

Reaction notes

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