Hydrochloric Acid → 5-chloro-3-hydroxy-3-(2-isopropylphenyl)-1,3-dihydro-2H-indol-2-one
Reaction equation
[Br:1][c:2]1[c:3]([CH:8]([CH3:9])[CH3:10])[cH:4][cH:5][cH:6][cH:7]1.[CH3:30][CH2:31][O:32][C:33](=[O:34])[CH3:35].[Cl:12][c:13]1[cH:14][c:15]2[c:19]([cH:20][cH:21]1)[NH:18][C:17](=[O:22])[C:16]2=[O:23].[ClH:24].[Mg:11].[O:25]1[CH2:26][CH2:27][CH2:28][CH2:29]1>>[c:2]1([C:16]2([OH:23])[c:15]3[cH:14][c:13]([Cl:12])[cH:21][cH:20][c:19]3[NH:18][C:17]2=[O:22])[c:3]([CH:8]([CH3:9])[CH3:10])[cH:4][cH:5][cH:6][cH:7]1Participants
7
Sources & evidence
- ORD record
- ord-c41d6f4024ff4c2bb84801ffd45c87ab
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (4/10)
Reaction notes
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