Hydrochloric Acid → N-{4-[(2-methylpropyl)amino]quinolin-3-yl}-3-(2-methyl-1,3-dioxolan-2-yl)propanamide

HRID 2156008Notes

Reaction equation

HRID 2156008 reaction equation
[C:47](=[O:48])([OH:49])[O-:50].[CH3:17][C:18]1([CH2:23][CH2:24][C:25](=[O:26])[OH:27])[O:19][CH2:20][CH2:21][O:22]1.[CH3:1][CH:2]([CH2:3][NH:4][c:5]1[c:6]([NH2:15])[cH:7][n:8][c:9]2[cH:10][cH:11][cH:12][cH:13][c:14]12)[CH3:16].[CH3:28][N:29]1[CH2:30][CH2:31][O:32][CH2:33][CH2:34]1.[CH3:36][N:37]([CH3:38])[CH2:39][CH2:40][CH2:41][N:42]=[C:43]=[N:44][CH2:45][CH3:46].[CH3:57][N:58]([CH3:59])[c:60]1[cH:61][cH:62][n:63][cH:64][cH:65]1.[ClH:35].[Na+:51].[O:52]=[CH:53][N:54]([CH3:55])[CH3:56]>>[CH3:1][CH:2]([CH2:3][NH:4][c:5]1[c:6]([NH:15][C:25]([CH2:24][CH2:23][C:18]2([CH3:17])[O:19][CH2:20][CH2:21][O:22]2)=[O:26])[cH:7][n:8][c:9]2[cH:10][cH:11][cH:12][cH:13][c:14]12)[CH3:16]

Participants

10

Reactant 9

HCID 313Hydrochloric AcidHCID 769Bicarbonate IonHCID 923Sodium ionHCID 6228DimethylformamideHCID 79724-MethylmorpholineHCID 142844-(Dimethylamino)pyridineHCID 159081-Ethyl-3-(3'-dimethylaminopropyl)carbodiimideHCID 109317243-(2-methyl-1,3-dioxolan-2-yl)propanoic AcidHCID 11298872N4-(2-methylpropyl)quinoline-3,4-diamine

Product 1

HCID 67052427N-{4-[(2-methylpropyl)amino]quinolin-3-yl}-3-(2-methyl-1,3-dioxolan-2-yl)propanamide

Sources & evidence

ORD record
ord-61ef1fd9304b46d08aa67ac71a7cbfeb
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (4/10)

Reaction notes

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