Dimethylformamide → 1-Phenyl-2-(trimethylsilyl)acetylene

HRID 2158726Notes

Reaction equation

HRID 2158726 reaction equation
[CH3:14][CH2:15][N:16]([CH2:17][CH3:18])[CH2:19][CH3:20].[CH3:8][Si:9]([CH3:10])([CH3:11])[C:12]#[CH:13].[Cu:67][I:68].[I:1][c:2]1[cH:3][cH:4][cH:5][cH:6][cH:7]1.[O:21]=[CH:22][N:23]([CH3:24])[CH3:25].[Pd:26]([Cl:27])[Cl:28].[c:29]1([P:30]([c:31]2[cH:32][cH:33][cH:34][cH:35][cH:36]2)[c:37]2[cH:38][cH:39][cH:40][cH:41][cH:42]2)[cH:43][cH:44][cH:45][cH:46][cH:47]1.[c:48]1([P:49]([c:50]2[cH:51][cH:52][cH:53][cH:54][cH:55]2)[c:56]2[cH:57][cH:58][cH:59][cH:60][cH:61]2)[cH:62][cH:63][cH:64][cH:65][cH:66]1>>[c:2]1([C:13]#[C:12][Si:9]([CH3:8])([CH3:10])[CH3:11])[cH:3][cH:4][cH:5][cH:6][cH:7]1

Participants

8

Reactant 7

HCID 6228DimethylformamideHCID 8471TriethylamineHCID 11575IodobenzeneHCID 11776Triphenylphosphine2×HCID 24290Palladium ChlorideHCID 24350Copper(1+) iodide; Copper(I) iodide; Cuprous iodide; Cuprous iodide (CuI)HCID 66111Trimethylsilylacetylene

Product 1

HCID 1374641-Phenyl-2-(trimethylsilyl)acetylene

Sources & evidence

ORD record
ord-111d758d0d8e4d54b1296dd11b19e26f
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (4/10)

Reaction notes

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