Tetrahydrofuran → N-{5-[(2-Chloro-4-pyrimidinyl)ethynyl]-2-fluorophenyl}-2,2,2-trifluoroacetamide
Reaction equation
[C:16](#[CH:17])[c:18]1[cH:19][cH:20][c:21]([F:31])[c:22]([NH:24][C:25]([C:26]([F:27])([F:28])[F:29])=[O:30])[cH:23]1.[CH2:32]1[O:33][CH2:34][CH2:35][CH2:36]1.[CH3:9][CH2:10][N:11]([CH2:12][CH3:13])[CH2:14][CH3:15].[Cl:1][c:2]1[n:3][cH:4][cH:5][c:6]([Cl:8])[n:7]1.[Cu:37][I:38]>>[Cl:1][c:2]1[n:3][cH:4][cH:5][c:6]([C:17]#[C:16][c:18]2[cH:19][cH:20][c:21]([F:31])[c:22]([NH:24][C:25]([C:26]([F:27])([F:28])[F:29])=[O:30])[cH:23]2)[n:7]1Participants
6
Reactant 5
Product 1
Sources & evidence
- ORD record
- ord-323a1fd09ec645b080cffd4214520b57
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (4/10)
Reaction notes
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