Chloride → 4-Amino-4-(1-(4-chlorophenyl)cyclobutyl]butan-1-ol
Reaction equation
[BH4-:25].[CH3:34][CH:35]([OH:36])[CH3:37].[CH:7]([Mg+:8])([CH3:9])[CH3:10].[Cl-:6].[Cl:12][c:13]1[cH:14][cH:15][c:16]([C:19]2([C:23]#[N:24])[CH2:20][CH2:21][CH2:22]2)[cH:17][cH:18]1.[Cl:1][CH2:2][CH2:3][CH2:4][OH:5].[ClH:27].[Mg:11].[Na+:26].[O:28]1[CH2:29][CH2:30][CH2:31][CH2:32]1.[OH2:33]>>[CH2:2]([CH2:3][CH2:4][OH:5])[CH:23]([C:19]1([c:16]2[cH:15][cH:14][c:13]([Cl:12])[cH:18][cH:17]2)[CH2:20][CH2:21][CH2:22]1)[NH2:24]Participants
12
Reactant 11
Product 1
Sources & evidence
- ORD record
- ord-63195f3d2a89415cb2f3ce7a6aaf8c58
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (10/10)
Reaction notes
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