Hydrochloric Acid → 1-(5-Bromo-2-fluorophenyl)ethanone

HRID 2322901Notes

Reaction equation

HRID 2322901 reaction equation
[Br:1][c:2]1[cH:3][cH:4][c:5]([F:11])[c:6]([C:7](=[O:8])[OH:9])[cH:10]1.[Br:38][c:39]1[cH:40][cH:41][c:42]([F:43])[c:44]([C:46]([N:47]([O:48][CH3:49])[CH3:50])=[O:51])[cH:45]1.[CH3:12][CH2:13][N:14]([CH2:15][CH3:16])[CH2:17][CH3:18].[CH3:20][N:21]([CH3:22])[CH2:23][CH2:24][CH2:25][N:26]=[C:27]=[N:28][CH2:29][CH3:30].[CH3:31][NH:32][O:33][CH3:34].[CH3:35][Mg:36][Cl:37].[CH3:55][N:56]([CH3:57])[c:58]1[cH:59][cH:60][n:61][cH:62][cH:63]1.[Cl:52][CH2:53][Cl:54].[ClH:19].[O:64]1[CH2:65][CH2:66][CH2:67][CH2:68]1>>[Br:1][c:2]1[cH:3][cH:4][c:5]([F:11])[c:6]([C:7](=[O:9])[CH3:12])[cH:10]1

Participants

11

Reactant 10

HCID 313Hydrochloric AcidHCID 6344DichloromethaneHCID 8028TetrahydrofuranHCID 8471TriethylamineHCID 14232N,O-DimethylhydroxylamineHCID 142844-(Dimethylamino)pyridineHCID 159081-Ethyl-3-(3'-dimethylaminopropyl)carbodiimideHCID 27363155-Bromo-2-fluorobenzoic acidHCID 606295205-bromo-2-fluoro-N-methoxy-N-methylbenzamideHCID 178418332HCID 178418332, compound

Product 1

HCID 226074761-(5-Bromo-2-fluorophenyl)ethanone

Sources & evidence

ORD record
ord-b1438a41d848443c9fef8e950fcb300a
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (10/10)

Reaction notes

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