Acetic Acid → 2-Bromo-6-fluorobenzaldehyde

HRID 2324455Notes

Reaction equation

HRID 2324455 reaction equation
[Br:1][c:2]1[cH:3][c:4]([F:8])[cH:5][cH:6][cH:7]1.[C:31]([O:32][CH3:33])([CH3:34])([CH3:35])[CH3:36].[CH2:25]1[CH2:27][CH2:26][CH2:28][O:29]1.[CH3:37][C:38](=[O:39])[OH:40].[CH:17]([NH:18][CH:19]([CH3:20])[CH3:21])([CH3:22])[CH3:23].[CH:9]([N-:10][CH:11]([CH3:12])[CH3:13])([CH3:14])[CH3:15].[ClH:24].[Li+:16].[O:41]=[CH:42][N:43]([CH3:44])[CH3:45].[OH2:30]>>[Br:1][c:2]1[c:3]([CH:28]=[O:29])[c:4]([F:8])[cH:5][cH:6][cH:7]1

Participants

11

Reactant 10

HCID 176Acetic AcidHCID 313Hydrochloric AcidHCID 962WaterHCID 6228DimethylformamideHCID 7912DiisopropylamineHCID 8028TetrahydrofuranHCID 140821-Bromo-3-fluorobenzeneHCID 15413tert-Butyl methyl etherHCID 28486Lithium ionHCID 5062348Diisopropylamide

Product 1

HCID 224739772-Bromo-6-fluorobenzaldehyde

Sources & evidence

ORD record
ord-c3a1bd52d5e3404fbd007a5934ff413a
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (10/10)

Reaction notes

Loading…