1,2-Dichloroethane → methyl 4-[4,4-difluoro-1-[3-methoxy-4-[N'-(2-methylphenyl)ureido]phenylacetyl]-2-pyrrolidinylmethoxy]benzoate
Reaction equation
[CH2:43]([Cl:44])[CH2:45][Cl:46].[CH3:20][O:21][c:22]1[cH:23][c:24]([CH2:39][C:40](=[O:41])[OH:42])[cH:25][cH:26][c:27]1[NH:28][C:29](=[O:30])[NH:31][c:32]1[c:33]([CH3:38])[cH:34][cH:35][cH:36][cH:37]1.[CH3:58][N:59]([c:60]1[cH:61][cH:62][n:63][cH:64][cH:65]1)[CH3:66].[CH3:72][CH2:73][O:74][C:75]([CH3:76])=[O:77].[ClH:47].[F:1][C:2]1([F:19])[CH2:3][CH:4]([CH2:7][O:8][c:9]2[cH:10][cH:11][c:12]([C:13](=[O:14])[O:15][CH3:16])[cH:17][cH:18]2)[NH:5][CH2:6]1.[O:67]=[CH:68][N:69]([CH3:70])[CH3:71].[OH:48][n:49]1[c:50]2[c:51]([cH:52][cH:53][cH:54][cH:55]2)[n:56][n:57]1>>[F:1][C:2]1([F:19])[CH2:3][CH:4]([CH2:7][O:8][c:9]2[cH:10][cH:11][c:12]([C:13](=[O:14])[O:15][CH3:16])[cH:17][cH:18]2)[N:5]([C:40]([CH2:39][c:24]2[cH:23][c:22]([O:21][CH3:20])[c:27]([NH:28][C:29](=[O:30])[NH:31][c:32]3[c:33]([CH3:38])[cH:34][cH:35][cH:36][cH:37]3)[cH:26][cH:25]2)=[O:41])[CH2:6]1Participants
9
Reactant 8
Product 1
Sources & evidence
- ORD record
- ord-d881fb0df318469da763a7cc1d300875
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (10/10)
Reaction notes
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