Hydrochloric Acid → 2-chloro-5-fluoro-N-{cis-4-[(methoxyacetyl)amino]cyclohexyl}nicotinamide
Reaction equation
[CH3:19][CH2:20][N:21]([CH2:22][CH3:23])[CH2:24][CH3:25].[CH3:26][O:27][CH2:28][C:29](=[O:30])[OH:31].[CH3:33][N:34]([CH3:35])[CH2:36][CH2:37][CH2:38][N:39]=[C:40]=[N:41][CH2:42][CH3:43].[CH3:54][N:55]([CH3:56])[CH:57]=[O:58].[ClH:32].[NH2:1][CH:2]1[CH2:3][CH2:4][CH:5]([NH:8][C:9]([c:10]2[c:11]([Cl:17])[n:12][cH:13][c:14]([F:16])[cH:15]2)=[O:18])[CH2:6][CH2:7]1.[OH:44][n:45]1[c:46]2[cH:47][cH:48][cH:49][cH:50][c:51]2[n:52][n:53]1>>[NH:1]([CH:2]1[CH2:3][CH2:4][CH:5]([NH:8][C:9]([c:10]2[c:11]([Cl:17])[n:12][cH:13][c:14]([F:16])[cH:15]2)=[O:18])[CH2:6][CH2:7]1)[C:29]([CH2:28][O:27][CH3:26])=[O:30]Participants
8
Reactant 7
Product 1
Sources & evidence
- ORD record
- ord-495ab1f117ff4fb2b52bc1882f4d0ce9
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (10/10)
Reaction notes
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