2-Aminothiazole → HCID 22315143, compound

HRID 289846Notes

Reaction equation

HRID 289846 reaction equation
[CH2:42]([Cl:43])[Cl:44].[CH3:50][N:51]([CH3:52])[CH:53]=[O:54].[CH:1]1([CH2:6][CH:7]([C:8](=[O:9])[OH:10])[c:11]2[cH:12][c:13]([O:19][CH3:20])[c:14]([O:17][CH3:18])[cH:15][cH:16]2)[CH2:2][CH2:3][CH2:4][CH2:5]1.[CH:33]([N:34]([CH2:35][CH3:36])[CH:37]([CH3:38])[CH3:39])([CH3:40])[CH3:41].[Cl:21][C:22]([C:23]([Cl:24])=[O:25])=[O:26].[NH2:27][c:28]1[s:29][cH:30][cH:31][n:32]1.[O:45]1[CH2:46][CH2:47][CH2:48][CH2:49]1>>[CH:1]1([CH2:6][CH:7]([C:8](=[O:10])[NH:27][c:28]2[s:29][cH:30][cH:31][n:32]2)[c:11]2[cH:12][c:13]([O:19][CH3:20])[c:14]([O:17][CH3:18])[cH:15][cH:16]2)[CH2:2][CH2:3][CH2:4][CH2:5]1

Participants

8

Reactant 7

HCID 21552-AminothiazoleHCID 6228DimethylformamideHCID 6344DichloromethaneHCID 8028TetrahydrofuranHCID 65578Oxalyl chlorideHCID 81531DiisopropylethylamineHCID 22315298HCID 22315298, compound

Product 1

HCID 22315143HCID 22315143, compound

Sources & evidence

ORD record
ord-b42edd31dcd74772b857c4f912387773
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (8/10)

Reaction notes

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