Hydrochloric Acid → [2-(4-Chloro-phenyl)-5,6-difluoro-benzoimidazol-1-yl]-cyclopentyl-acetic acid
Reaction equation
[CH2:1]([N:2]([N:3]=[O:4])[C:9]([CH:10]([CH:11]1[CH2:12][CH2:13][CH2:14][CH2:15]1)[n:16]1[c:17](-[c:27]2[cH:28][cH:29][c:30]([Cl:33])[cH:31][cH:32]2)[n:18][c:19]2[c:20]1[cH:21][c:22]([F:26])[c:23]([F:25])[cH:24]2)=[O:34])[c:5]1[cH:6][cH:7][cH:8][cH:35][cH:36]1.[CH3:49][CH2:50][O:51][C:52](=[O:53])[CH3:54].[ClH:42].[Li+:39].[O:43]1[CH2:44][CH2:45][CH2:46][CH2:47]1.[OH-:38].[OH2:37].[OH2:48].[OH:40][OH:41]>>[C:9]([CH:10]([CH:11]1[CH2:12][CH2:13][CH2:14][CH2:15]1)[n:16]1[c:17](-[c:27]2[cH:28][cH:29][c:30]([Cl:33])[cH:31][cH:32]2)[n:18][c:19]2[c:20]1[cH:21][c:22]([F:26])[c:23]([F:25])[cH:24]2)(=[O:34])[OH:37]Participants
9
Reactant 8
Product 1
Sources & evidence
- ORD record
- ord-445c2e367ffa4f9aade48b92eff76c03
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (8/10)
Reaction notes
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