Potassium Carbonate → HCID 18177044, compound

HRID 394499Notes

Reaction equation

HRID 394499 reaction equation
[OH:1][CH:2]1[CH2:7][CH2:6][NH:5][CH2:4][CH2:3]1.C(=O)([O-])[O-].[K+].[K+].I[CH2:15][CH2:16][CH2:17][CH2:18][CH2:19][CH2:20][CH3:21]>CN(C)C=O.C(OCC)(=O)C>[CH2:15]([N:5]1[CH2:6][CH2:7][CH:2]([OH:1])[CH2:3][CH2:4]1)[CH2:16][CH2:17][CH2:18][CH2:19][CH2:20][CH3:21]

Participants

6

Reactant 3

HCID 11430Potassium CarbonateHCID 202741-IodoheptaneHCID 79341Piperidin-4-ol

Product 1

HCID 18177044HCID 18177044, compound

Reagents, catalysts & solvents 2

HCID 6228DimethylformamideSolventHCID 8857Ethyl AcetateSolvent

Procedure

4-Hydroxypiperidine was dissolved in N,N-dimethylformamide (20 ml) and treated with potassium carbonate (1.5 g, 10.8 mmol) and 1-iodoheptane (1.8 ml, 11.3 mmol). After stirring for 2 h the mixture was diluted with ethyl acetate, washed with water, brine, dried and evaporated.

Workup

  1. washwashed with water, brine
  2. customdried
  3. customevaporated

Sources & evidence

ORD record
ord-4185a8181a894963a00059057df25bf8
Source dataset
uspto-grants-2003_08
Patent number
US06602882B1

Reaction notes

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