Dimethylformamide → Ethyl 1-benzylpiperidine-4-carboxylate

HRID 677412Notes

Reaction equation

HRID 677412 reaction equation
[Br:19][CH2:20][c:21]1[cH:22][cH:23][cH:24][cH:25][cH:26]1.[CH3:12][CH2:13][N:14]([CH2:15][CH3:16])[CH2:17][CH3:18].[CH3:27][N:28]([CH3:29])[CH:30]=[O:31].[NH:1]1[CH2:2][CH2:3][CH:4]([C:7](=[O:8])[O:9][CH2:10][CH3:11])[CH2:5][CH2:6]1>>[N:1]1([CH2:20][c:21]2[cH:22][cH:23][cH:24][cH:25][cH:26]2)[CH2:2][CH2:3][CH:4]([C:7](=[O:8])[O:9][CH2:10][CH3:11])[CH2:5][CH2:6]1

Participants

5

Reactant 4

HCID 6228DimethylformamideHCID 7498Benzyl BromideHCID 8471TriethylamineHCID 70770Ethyl 4-piperidinecarboxylate

Product 1

HCID 90423Ethyl 1-benzylpiperidine-4-carboxylate

Sources & evidence

ORD record
ord-b0aa0bd2cc194872b77ef2d5acdfef61
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (3/10)

Reaction notes

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