Chloride → 5-(6-Chloropyridazin-3-yl)-6-(2,4-difluorophenyl)imidazo[2,1-b]oxazole
Reaction equation
[CH2:32]1[O:33][CH2:34][CH2:35][CH2:36]1.[Cl-:37].[Cl-:39].[Cl:117][CH2:118][Cl:119].[Cl:18][c:19]1[n:20][n:21][c:22]([I:25])[cH:23][cH:24]1.[ClH:31].[F:1][c:2]1[c:3](-[c:9]2[n:10][c:11]3[o:12][cH:13][cH:14][n:15]3[c:16]2[I:17])[cH:4][cH:5][c:6]([F:8])[cH:7]1.[O:26]=[CH:27][N:28]([CH3:29])[CH3:30].[Zn+2:38].[cH:40]1[cH:41][cH:42][c:43]([P:44]([Pd:45]([P:46]([c:47]2[cH:48][cH:49][cH:50][cH:51][cH:52]2)([c:53]2[cH:54][cH:55][cH:56][cH:57][cH:58]2)[c:59]2[cH:60][cH:61][cH:62][cH:63][cH:64]2)([P:65]([c:66]2[cH:67][cH:68][cH:69][cH:70][cH:71]2)([c:72]2[cH:73][cH:74][cH:75][cH:76][cH:77]2)[c:78]2[cH:79][cH:80][cH:81][cH:82][cH:83]2)[P:84]([c:85]2[cH:86][cH:87][cH:88][cH:89][cH:90]2)([c:91]2[cH:92][cH:93][cH:94][cH:95][cH:96]2)[c:97]2[cH:98][cH:99][cH:100][cH:101][cH:102]2)([c:103]2[cH:104][cH:105][cH:106][cH:107][cH:108]2)[c:109]2[cH:110][cH:111][cH:112][cH:113][cH:114]2)[cH:115][cH:116]1>>[F:1][c:2]1[c:3](-[c:9]2[n:10][c:11]3[o:12][cH:13][cH:14][n:15]3[c:16]2-[c:22]2[n:21][n:20][c:19]([Cl:18])[cH:24][cH:23]2)[cH:4][cH:5][c:6]([F:8])[cH:7]1Participants
10
Reactant 9
Product 1
Sources & evidence
- ORD record
- ord-df5a8c6d19794eefb8147fe9a7302336
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (3/10)
Reaction notes
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