Chloride → 4-(4-Fluorophenyl)but-3-yn-1-ol

HRID 697596Notes

Reaction equation

HRID 697596 reaction equation
[Br:21][c:22]1[cH:23][cH:24][c:25]([F:28])[cH:26][cH:27]1.[CH2:29]([CH2:30][C:31]#[CH:32])[OH:33].[CH3:34][CH2:35][N:36]([CH2:37][CH3:38])[CH2:39][CH3:40].[Cl-:1].[Cu:41][I:42].[c:2]1([P:3]([c:4]2[cH:5][cH:6][cH:7][cH:8][cH:9]2)[c:10]2[cH:11][cH:12][cH:13][cH:14][cH:15]2)[cH:16][cH:17][cH:18][cH:19][cH:20]1>>[c:22]1([C:32]#[C:31][CH2:30][CH2:29][OH:33])[cH:23][cH:24][c:25]([F:28])[cH:26][cH:27]1

Participants

7

Reactant 6

HCID 312ChlorideHCID 8471TriethylamineHCID 99931-Bromo-4-fluorobenzeneHCID 11776TriphenylphosphineHCID 135663-Butyn-1-OLHCID 24350Copper(1+) iodide; Copper(I) iodide; Cuprous iodide; Cuprous iodide (CuI)

Product 1

HCID 124784404-(4-Fluorophenyl)but-3-yn-1-ol

Sources & evidence

ORD record
ord-ea3c0f680e0d425b90cd3b76fac523e5
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (3/10)

Reaction notes

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