Tetrahydrofuran → 3,4-Dihydro-4,4-dimethyl-6-(trimethlsilanyl)ethynylspiro[2H-1-benzopyran-2,1'-cyclopropane]

HRID 828866Notes

Reaction equation

[Br:1][c:2]1[cH:3][cH:4][c:5]2[c:6]([cH:15]1)[C:7]([CH3:13])([CH3:14])[CH2:8][C:9]1([O:10]2)[CH2:11][CH2:12]1.[CH2:16]([N:17]([CH2:18][CH3:19])[CH2:20][CH3:21])[CH3:22].[CH3:23][Si:24]([CH3:25])([CH3:26])[C:27]#[CH:28].[Cu:29][I:30].[O:72]1[CH2:73][CH2:74][CH2:75][CH2:76]1.[Pd:31]([Cl:32])[Cl:33].[c:34]1([P:35]([c:36]2[cH:37][cH:38][cH:39][cH:40][cH:41]2)[c:42]2[cH:43][cH:44][cH:45][cH:46][cH:47]2)[cH:48][cH:49][cH:50][cH:51][cH:52]1.[c:53]1([P:54]([c:55]2[cH:56][cH:57][cH:58][cH:59][cH:60]2)[c:61]2[cH:62][cH:63][cH:64][cH:65][cH:66]2)[cH:67][cH:68][cH:69][cH:70][cH:71]1>>[c:2]1([C:28]#[C:27][Si:24]([CH3:23])([CH3:25])[CH3:26])[cH:3][cH:4][c:5]2[c:6]([cH:15]1)[C:7]([CH3:13])([CH3:14])[CH2:8][C:9]1([O:10]2)[CH2:11][CH2:12]1