Triethylamine → Benzene, 1-(trifluoromethoxy)-3-[2-(trimethylsilyl)ethynyl]-

HRID 933978Notes

Reaction equation

HRID 933978 reaction equation
[Br:8][c:9]1[cH:10][c:11]([O:15][C:16]([F:17])([F:18])[F:19])[cH:12][cH:13][cH:14]1.[CH3:1][CH2:2][N:3]([CH2:4][CH3:5])[CH2:6][CH3:7].[CH3:20][Si:21]([CH3:22])([CH3:23])[C:24]#[CH:25].[CH3:26][CH2:27][O:28][C:29](=[O:30])[CH3:31].[Cu:32][I:33].[Pd:34]([Cl:35])[Cl:36].[c:37]1([P:38]([c:39]2[cH:40][cH:41][cH:42][cH:43][cH:44]2)[c:45]2[cH:46][cH:47][cH:48][cH:49][cH:50]2)[cH:51][cH:52][cH:53][cH:54][cH:55]1.[c:56]1([P:57]([c:58]2[cH:59][cH:60][cH:61][cH:62][cH:63]2)[c:64]2[cH:65][cH:66][cH:67][cH:68][cH:69]2)[cH:70][cH:71][cH:72][cH:73][cH:74]1>>[c:9]1([C:25]#[C:24][Si:21]([CH3:20])([CH3:22])[CH3:23])[cH:10][c:11]([O:15][C:16]([F:17])([F:18])[F:19])[cH:12][cH:13][cH:14]1

Participants

8

Reactant 7

HCID 8471TriethylamineHCID 8857Ethyl AcetateHCID 11776Triphenylphosphine2×HCID 24290Palladium ChlorideHCID 24350Copper(1+) iodide; Copper(I) iodide; Cuprous iodide; Cuprous iodide (CuI)HCID 66111TrimethylsilylacetyleneHCID 5199641-Bromo-3-(trifluoromethoxy)benzene

Product 1

HCID 67047416Benzene, 1-(trifluoromethoxy)-3-[2-(trimethylsilyl)ethynyl]-

Sources & evidence

ORD record
ord-b0c513d2d21e4b54bd32c617f3051f45
Source dataset
Validation data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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