Acetate → 5-Benzyloxy-3,4'-difluorostilbene

HRID 93952Notes

Reaction equation

HRID 93952 reaction equation
[CH2:1]([c:2]1[cH:3][cH:4][cH:5][cH:6][cH:7]1)[O:8][c:9]1[cH:10][c:11]([F:16])[cH:12][c:13]([Br:15])[cH:14]1.[CH3:48][CH2:49][N:50]([CH2:51][CH3:52])[CH2:53][CH3:54].[CH3:70][CH2:71][O:72][C:73]([CH3:74])=[O:75].[ClH:55].[F:39][c:40]1[cH:41][cH:42][c:43]([CH:44]=[CH2:45])[cH:46][cH:47]1.[O-:62][C:63]([CH3:64])=[O:65].[O-:66][C:67]([CH3:68])=[O:69].[O:56]=[CH:57][N:58]([CH3:59])[CH3:60].[Pd+2:61].[c:17]1([CH3:18])[cH:19][cH:20][cH:21][cH:22][c:23]1[P:24]([c:25]1[cH:26][cH:27][cH:28][cH:29][c:30]1[CH3:31])[c:32]1[cH:33][cH:34][cH:35][cH:36][c:37]1[CH3:38]>>[CH2:1]([c:2]1[cH:3][cH:4][cH:5][cH:6][cH:7]1)[O:8][c:9]1[cH:10][c:11]([F:16])[cH:12][c:13]([CH:45]=[CH:44][c:43]2[cH:42][cH:41][c:40]([F:39])[cH:47][cH:46]2)[cH:14]1

Participants

10

Reactant 9

HCID 175Acetate2×HCID 313Hydrochloric AcidHCID 6228DimethylformamideHCID 8471TriethylamineHCID 8857Ethyl AcetateHCID 678834-FluorostyreneHCID 80271Tri-o-tolylphosphineHCID 105144Allyl(1,3-bis(2,6-diisopropylphenyl)imidazol-2-ylidene)chloropalladium(II)HCID 112545161-(Benzyloxy)-3-bromo-5-fluorobenzene

Product 1

HCID 687418575-Benzyloxy-3,4'-difluorostilbene

Sources & evidence

ORD record
ord-f8fbde2679ab4019b8b5775c62c8e78c
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (2/10)

Reaction notes

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